The health status of millions of people is projected to be affected through, for example, increases in malnutrition; increased deaths, diseases and injury due to extreme weather events; increased burden of diarrhoeal diseases; increased frequency of cardio-respiratory diseases due to higher concentrations of ground-level ozone in urban areas related to climate change; and the altered spatial distribution of some infectious diseases. {WGI 7.4, Box 7.4; WGII 8.ES, 8.2, 8.4, SPM}; Climate change is projected to bring some benefits in temperate areas, such as fewer deaths from cold exposure, and some mixed effects such as changes in range and transmission potential of malaria in Africa. Overall it is expected that benefits will be outweighed by the negative health effects of rising temperatures, especially in developing countries. {WGII 8.4, 8.7, 8.ES, SPM}; Critically important will be factors that directly shape the health of populations such as education, health care, public health initiatives, and infrastructure and economic development. {WGII 8.3, SPM} (IPCC, 2014)